Diagnostic Histopathology
Volume 14, Issue 1 , Pages 28-37 , January 2008

Spitz tumours

References 

  1. Spitz S. Melanomas of childhood. Am J Pathol. 1948;24:591–609
  2. Troxel DB. An insurer’s perspective on error and loss in pathology. Arch Pathol Lab Med. 2005;129:1234–1236
  3. Orchard DC, Dowling JP, Kelly JW. Spitz naevi misdiagnosed as melanoma: prevalence and clinical profile. Australas J Dermatol. 1997;38:12–14
  4. Barnhill RL, Argenyi ZB, From L, et al. Atypical Spitz nevi/tumors: lack of consensus for diagnosis, discrimination from melanoma and prediction of outcome. Hum Pathol. 1999;30:513–520
  5. Spatz A, Calonje E, Handfield-Jones S, Barnhill R. Spitz tumors in children; A grading system for risk stratification. Arch Dermatol. 1999;135:282–285
  6. Barnhill RL. The Spitzoid lesion; the importance of atypical variants and risk assessment. Am J Dermatopathol. 2006;28:75–83
  7. Caso EM, Grin-Jorgensen CM, Grant-Kels JM. Spitz nevus. J Am Acad Dermatol. 1992;27:901–913
  8. Cesinaro AM, Foroni M, Sighinolfi P, Migaldi M, Trentini GP. Spitz nevus is relatively frequent on adults: a clinicopathologic study of 247 cases related to patient’s age. Am J Dermatopathol. 2005;27:469–475
  9. Seehra J, Sen P, Lloyd R, Sloan P. Intraoral Spitz naevus: a case report. Int J Oral Maxillofac Surg. 2007;36:661–662
  10. Aoyagi S, Sato-Matsumura KC, Akiyama M, Tanimura S, Shibaki H, Shimizu H. Spitz naevus of the glans penis; an unusual location. Acta Dermatol Venereol. 2004;84:324–325
  11. Dorji T, Cavazza A, Nappi O, Rosai J. Spitz nevus of the tongue with pseudoepitheliomatous hyperplasia: report of three cases of a pseudomalignant condition. Am J Surg Pathol. 2002;26:774–777
  12. Dawe RS, Wainwright NJ, Evans AT, Lowe JG. Multiple widespread eruptive Spitz nevi. Br J Dermatol. 1998;138:872–874
  13. Busam KJ, Barnhill RL. Intraepidermal Spitz tumor with prominent pagetoid spread. Am J Surg Pathol. 1995;19:1061–1067
  14. Binder S, Asnog C, Paul E, Cochran A. The histology and differential diagnosis of Spitz nevus. Semin Diag Pathol. 1993;10:36–46
  15. Stern JB, Haupt HM. Pagetoid melanocytosis: tease or tocsin?. Semin Diagn Pathol. 1998;15:225–229
  16. Kamino H, Misheloff E, Ackerman A, Flotte T, Greco M. Eosinophilic globules in Spit’s nevi. New findings and a diagnostic sign. Am J Surg Pathol. 1979;1:319–324
  17. Arbuckle S, Weedon D. Eosinophilic globules in the Spitz nevus. J Am Acad Dermatol. 1982;7:324–327
  18. Weedon D. The Spitz nevus. Clin Oncol. 1984;3:493–507
  19. Li LX, Crotty KA, McCarthy SW, Palmer AA, Kril JJ. A zonal comparison of MIB1-Ki67 immunoreactivity in benign and malignant melanocytic lesions. Am J Dermatopathol. 2000;22:489–495
  20. Bergman R, Malkin L, Sabo E, Kerner H. MIB-1 monoclonal antibody to determine proliferative activity of Ki67 antigen as an adjunct to histopathologic differential diagnosis of Spitz nevi. J Am Acad Dermatol. 2001;44:500–504
  21. Howat AJ, Variend S. Lymphatic invasion in Spitz nevi. Am J Surg Pathol. 1985;9:125–128
  22. Harvell JD, Meehan SA, LeBoit PE. Spitz’s nevi with halo reaction: a histopathologic study of 17 cases. J Cutan Pathol. 1997;24:611–619
  23. Liu J, Cohen PR, Farhood A. Hyalinising Spitz nevus: spindle and epithelioid cell nevus with paucicellular collagenous stroma. South Med J. 2004;97:102–106
  24. Burg G, Kempf W, Hochii M, Huwyler T, Panizzon RG. “Tubular” epithelioid cell nevus: a new variant of Spitz’s naevus. J Cutan Pathol. 1998;25:475–478
  25. Clarke B, Essa A, Chetty R. Plexiform Spitz nevus. Int J Surg Pathol. 2002;10:69–73
  26. Hoang MP. Myxoid Spitz naevus. J Cutan Pathol. 2003;30:566–568
  27. Diaz-Cascajo C, Borhi S, Weyers W. Angiomatoid Spitz nevus: a distinct variant of desmoplastic Spitz nevus with prominent vasculature. Am J Dermatopathol. 2000;22:135–139
  28. Mones JM, Ackerman AB. Melanomas in prepubescent children: review comprehensively, critique historically, criteria diagnostically and course biologically. Am J Dermatopathol. 2003;25:223–238
  29. Fabrisi G, Massi G. Spitzoid malignant melanoma in teenagers: an entity with no better prognosis than that of other forms of melanoma. Histopathology. 2001;38:448–453
  30. Pol-Rodriquez M, Lees S, Silvers DN, Celebi JT. Influence of age on survival in childhood Spitzoid melanomas. Cancer. 2007;109:1579–1583
  31. Okun MR. Silhouette symmetry: an unsupportable histologic criterion for distinguishing Spitz nevi and compound nevi form malignant melanoma. Arch Pathol Lab Med. 1997;121:48–53
  32. Okun MR. Histological demarcation of lateral borders: an unsupportable criterion for distinguishing malignant melanoma from Spitz naevus and compound naevus. Histopathology. 1998;33:158–162
  33. Hantschke M, Bastian BC, LeBoit PE. Consumption of the epidermis: a diagnostic criterion for the differential diagnosis of melanoma and Spitz nevus. Am J Surg Pathol. 2004;28:1621–1625
  34. Walsh N, Crotty K, Palmer A, McCarty S. Spitz nevus versus Spitzoid malignant melanoma: an evaluation of the current distinguishing histopathologic criteria. Hum Pathol. 1998;29:1105–1112
  35. Crotty KA, Scolyer RA, Li L, Palmer AA, Wang L, McCarthy SW. Spitz naevus versus Spitzoid melanoma: when and how can they be distinguished?. Pathology. 2002;34:6–12
  36. Barnhill RL. The Spitzoid lesion: rethinking Spitz tumors, atypical variants, ‘Spitzoid melanoma’ and risk assessment. Mod Pathol. 2006;19(suppl 2):S21–S33
  37. Lee DA, Cohen JA, Twadell WS, et al. Are all types of melanoma the same? Spitzoid melanoma is a distinct subtype of melanoma. Cancer. 2006;106:907–913
  38. Gill M, Cohen J, Renwick N, Mones JM, Silvers DN, Celebi JT. Genetic similarities between Spitz nevus and Spitzoid melanoma in children. Cancer. 2004;101:2636–2640
  39. Smith KJ, Barrett TL, Skelton HG, Lupton GP, Graham JH. Spindle and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus). Am J Surg Pathol. 1989;13:931–939
  40. Mooi WJ, Krausz T. Spitz nevus versus Spitzoid melanoma: diagnostic difficulties, conceptual controversies. Adv Anat Pathol. 2006;13:147–156
  41. Urso C. A new perspective for Spitz tumors?. Am J Dermatopathol. 2005;27:364–366
  42. Li LX, Crotty KA, Palmer AA, et al. Argyrophilic staining of nucleolar organizer region count and morphometry in benign and malignant melanocytic lesions. Am J Dermatopathol. 2003;25:190–197
  43. Skowronek J, Warchol JB, Karas Z, Krenz RM. Significance of DNA ploidy measurements in Spitz naevi. Pol J Pathol. 2000;51:45–50
  44. Li LX, Crotty KA, Palmer AA, et al. Differentiating benign nevi from malignant melanoma using DNA microdensitometry and karyometry and maturation; a zonal comparison, correlation and multivariate analysis. Anal Quant Cytol Histol. 2002;24:234–243
  45. Nagasaka T, Lai R, Medeiros LJ, et al. Cyclin D1 overexpression in Spitz nevi: an immunohistochemical study. Am J Dermatopathol. 1999;21:15–20
  46. Kanter-Lewensohn L, Hedblad MA, Wejde J, Larsson O. Immunohistochemical markers for distinguishing Spitz nevi from malignant melanomas. Mod Pathol. 1997;10:917–920
  47. Bastian BC, Wesselmann U, Pinkel D, LeBoit PE. Molecular cytogenetic analysis of Spitz nevi shows clear differences to melanoma. J Invest Dermatol. 1999;113:1065–1069
  48. Maldonado JL, Timmerman L, Fridlyand J, Bastian BC. Mechanisms of cell-cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway. Am J Pathol. 2004;164:1783–1787
  49. Su LD, Fullen DR, Sondak VK, Johnson TM, Lowe L. Sentinel lymph node biopsy for patients with problematic Spitzoid melanocytic lesions: a report on 18 patients. Cancer. 2003;97:499–507
  50. Urso C, Borgognoni L, Saieva C, et al. Sentinel lymph node biopsy in patients with “atypical Spitz tumors”. A report on 12 cases. Hum Pathol. 2006;37:816–823

PII: S1756-2317(07)00120-X

doi: 10.1016/j.mpdhp.2007.11.002

Diagnostic Histopathology
Volume 14, Issue 1 , Pages 28-37 , January 2008

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