Diagnostic Histopathology
Volume 15, Issue 3 , Pages 142-150 , March 2009

How to make tissue microarrays

References 

  1. Kononen J, Bubendorf L, Kallioniemi A, et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med. 1998;4:844–847
  2. Yan P, Seelentag W, Bachmann A, Bosman FT. An agarose matrix facilitates sectioning of tissue microarray blocks. J Histochem Cytochem. 2007;55:21–24
  3. Packeisen J, Buerger H, Krech R, Boecker W. Tissue microarrays: a new approach for quality control in immunohistochemistry. J Clin Pathol. 2002;55:613–615
  4. Hsu FD, Nielsen TO, Alkushi A, et al. TMAs are an effective quality assurance tool for diagnostic immunohistochemistry. Mod Pathol. 2002;15:1374–1380
  5. Fitzgibbons PL, Murphy DA, Dorfman DM, Roche PC, Tubbs RR. Interlaboratory comparison of immunohistochemical testing for HER2: results of the 2004 and 2005 College of American Pathologists HER2 Immunohistochemistry Tissue Microarray Survey. Arch Pathol Lab Med. 2006;130:1440–1445
  6. Chung GG, Zerkowski MP, Ghosh S, Camp RL, Rimm DL. Quantitative analysis of estrogen receptor heterogeneity in breast cancer. Lab Invest. 2007;87:662–669
  7. Dorfman DM, Bui MM, Tubbs RR, et al., College of American Pathologists Cell Markers Committee  The CD117 immunohistochemistry tissue microarray survey for quality assurance and interlaboratory comparison: a College of American Pathologists Cell Markers Committee Study. Arch Pathol Lab Med. 2006;130:779–782
  8. Mengel M, Hebel K, Kreipe H, von Wasielewski R. Standardized on-slide control for quality assurance in the immunohistochemical assessment of therapeutic target molecules in breast cancer. Breast J. 2005;11:34–40
  9. Hammer AS, Dietz HH, Hamilton-Dutoit S. Immunohistochemical detection of 3 viral infections in paraffin-embedded tissue from mink (Mustela vison): a tissue-microarray-based study. Can J Vet Res. 2007;71:8–13
  10. Borel N, Mukhopadhyay S, Kaiser C, et al. Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection. BMC Infect Dis. 2006;6:152
  11. Chan JK, Wong CS, Ku WT, Kwan MY. Reflections on the use of controls in immunohistochemistry and proposal for application of a multitissue spring-roll control block. Ann Diagn Pathol. 2000;4:329–336
  12. Wan WH, Fortuna MB, Furmanski P. A rapid and efficient method for testing immunohistochemical reactivity of monoclonal antibodies against multiple tissue samples simultaneously. J Immunol Methods. 1987;103:121–129
  13. Howat WJ, Warford A, Mitchell JN, Clarke KF, Conquer JS, McCafferty J. Resin tissue microarrays: a universal format for immunohistochemistry. J Histochem Cytochem. 2005;53:1189–1197
  14. Zhou L, Hodeib M, Abad JD, Mendoza L, Kore AR, Hu Z. New tissue microarray technology for analyses of gene expression in frozen pathological samples. Biotechniques. 2007;43:101–105
  15. Schoenberg Fejzo M, Slamon DJ. Frozen tumor tissue microarray technology for analysis of tumor RNA, DNA, and proteins. Am J Pathol. 2001;159:1645–1650
  16. Kyläniemi M, Koskinen M, Karhunen P, Rantala I, Peltola J, Haapasalo H. A novel frozen brain tissue array technique: immunohistochemical detection of neuronal paraneoplastic autoantibodies. Neuropathol Appl Neurobiol. 2004;30:39–45
  17. Waterworth A, Hanby A, Speirs V. A novel cell array technique for high-throughput, cell-based analysis. In Vitro Cell Dev Biol Anim. 2005;41:185–187
  18. Wirth GJ, Schandelmaier K, Smith V, Burger AM, Fiebig HH. Microarrays of 41 human tumor cell lines for the characterization of new molecular targets: expression patterns of cathepsin B and the transferrin receptor. Oncology. 2006;71:86–94
  19. Ferrer B, Bermudo R, Thomson T, et al. Paraffin-embedded cell line microarray (PECLIMA): development and validation of a high-throughput method for antigen profiling of cell lines. Pathobiology. 2005;72:225–232
  20. Andersson AC, Strömberg S, Bäckvall H, et al. Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics. J Histochem Cytochem. 2006;54:1413–1423
  21. Wen CH, Su YC, Wang SL, Yang SF, Chai CY. Application of the microarray technique to cell blocks. Acta Cytol. 2007;51:42–46
  22. Egervari K, Szollosi Z, Nemes Z. Tissue microarray technology in breast cancer HER2 diagnostics. Pathol Res Pract. 2007;203:169–177
  23. Skacel M, Siva A, Xu B, Tubbs RR. From array to array: confirmation of genomic gains and losses discovered by array-based comparative genomic hybridization utilizing fluorescence in situ hybridization on tissue microarrays. J Mol Histol. 2007;38:135–140
  24. Dubé V, Grigull J, DeSouza LV, et al. Verification of endometrial tissue biomarkers previously discovered using mass spectrometry-based proteomics by means of immunohistochemistry in a tissue microarray format. J Proteome Res. 2007;6:2648–2655
  25. Bubendorf L, Kolmer M, Kononen J, et al. Hormone therapy failure in human prostate cancer: analysis by complementary DNA and tissue microarrays. J Natl Cancer Inst. 1999;91:1758–1764
  26. Hewitt SM. The application of tissue microarrays in the validation of microarray results. Meth Enzymol. 2006;410:400–415
  27. Kallioniemi OP, Wagner U, Kononen J, Sauter G. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet. 2001;10:657–662
  28. Lorente Garín JA, Lloreta Trull J, Allepuz Losa C, Plaza Mas L, Rioja Sanz LA, Gelabert Mas A. Development of a tissue microarray (TMA) for immunohistochemical study of molecular expression profiling in prostate cancer (Part 1). Actas Urol Esp. 2006;30:25–32
  29. Venkataraman G, Ananthanaranayanan V. Tissue microarrays: Potential in the Indian subcontinent. Indian J Cancer. 2005;42:9–14
  30. Henriksen KL, Rasmussen BB, Lykkesfeldt AE, Møller S, Ejlertsen B, Mouridsen HT. Semi-quantitative scoring of potentially predictive markers for endocrine treatment of breast cancer: a comparison between whole sections and tissue microarrays. J Clin Pathol. 2007;60:397–404
  31. Chen Wei-Chang, Lin Mao-Song, Zhang Bao-Feng, et al. Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray. World J Gastroenterol. 2007;13:699–708
  32. Richani K, Romero R, Kim YM, et al. Tissue microarray: an effective high-throughput method to study the placenta for clinical and research purposes. J Matern Fetal Neonatal Med. 2006;19:509–515
  33. Goldstine J, Seligson DB, Beizai P, Miyata H, Vinters HV. Tissue microarrays in the study of non-neoplastic disease of the nervous system. J Neuropathol Exp Neurol. 2002;61:653–662
  34. Torhorst J, Bucher C, Kononen J, et al. Tissue microarrays for rapid linking of molecular changes to clinical endpoints. Am J Pathol. 2001;159:2249–2256
  35. Sauter G, Mirlacher M. Tissue microarrays for predictive molecular pathology. J Clin Pathol. 2002;55:575–576
  36. Kyndi M, Sørensen FB, Knudsen H, et al. Tissue microarrays compared with whole sections and biochemical analyses. A subgroup analysis of DBCG 82 b&c. Acta Oncol. 2008;47:591–599
  37. Hoos A, Cordon-Cardo C. Tissue microarray profiling of cancer specimens and cell lines: Opportunities and limitations. Lab Invest. 2001;81:1331–1338
  38. Hoos A, Urist MJ, Stojadinovic A, et al. Validation of tissue microarrays for immunohistochemical profiling of cancer specimens using the example of human fibroblastic tumors. Am J Pathol. 2001;158:1245–1251
  39. Gillett CE, Springall RJ, Barnes DM, Hanby AM. Multiple tissue core arrays in histopathology research: a validation study. J Pathol. 2000;192:549–553
  40. Leversha MA, Fielding P, Watson S, Gosney JR, Field JK. Expression of p53, pRB, and p16 in lung tumours: a validation study on tissue microarrays. J Pathol. 2003;200:610–619
  41. Boone J, van Hillegersberg R, van Diest PJ, Offerhaus GJ, Rinkes IH, Kate FJ. Validation of tissue microarray technology in squamous cell carcinoma of the esophagus. Virchows Arch. 2008;452:507–514
  42. Keller SM, Keller BC, Grest P, Börger CT, Guscetti F. Validation of tissue microarrays for immunohistochemical analyses of canine lymphomas. J Vet Diagn Invest. 2007;19:652–659
  43. Singh SS, Mehedint DC, Ford OH, Maygarden SJ, Ruiz B, Mohler JL. Feasibility of constructing tissue microarrays from diagnostic prostate biopsies. Prostate. 2007;67:1011–1018
  44. Fons G, Hasibuan SM, van der Velden J, ten Kate FJ. Validation of tissue microarray technology in endometrioid cancer of the endometrium. J Clin Pathol. 2007;60:500–503
  45. Gomaa W, Ke Y, Fujii H, Helliwell T. Tissue microarray of head and neck squamous carcinoma: validation of the methodology for the study of cutaneous fatty acid-binding protein, vascular endothelial growth factor, involucrin and Ki-67. Virchows Arch. 2005;447:701–709
  46. Engellau J, Bendahl PO, Persson A, et al. Improved prognostication in soft tissue sarcoma: independent information from vascular invasion, necrosis, growth pattern, and immunostaining using whole-tumor sections and tissue microarrays. Hum Pathol. 2005;36:994–1002
  47. Bhargava R, Lal P, Chen B. Feasibility of using tissue microarrays for the assessment of HER-2 gene amplification by fluorescence in situ hybridization in breast carcinoma. Diagn Mol Pathol. 2004;13:213–216
  48. Rosen DG, Huang X, Deavers MT, Malpica A, Silva EG, Liu J. Validation of tissue microarray technology in ovarian carcinoma. Mod Pathol. 2004;17:790–797
  49. Van den Eynden GG, Van der Auwera I, Van Laere S, et al. Validation of a tissue microarray to study differential protein expression in inflammatory and non-inflammatory breast cancer. Breast Cancer Res Treat. 2004;85:13–22
  50. Pacifico MD, Grover R, Richman P, Daley F, Wilson GD. Validation of tissue microarray for the immunohistochemical profiling of melanoma. Melanoma Res. 2004;14:39–42
  51. Griffin MC, Robinson RA, Trask DK. Validation of tissue microarrays using p53 immunohistochemical studies of squamous cell carcinoma of the larynx. Mod Pathol. 2003;16:1181–1188
  52. Chen B, van den Brekel MW, Buschers W, Balm AJ, van Velthuysen ML. Validation of tissue array technology in head and neck squamous cell carcinoma. Head Neck. 2003;25:922–930
  53. Jourdan F, Sebbagh N, Comperat E, et al. Tissue microarray technology: validation in colorectal carcinoma and analysis of p53, hMLH1, and hMSH2 immunohistochemical expression. Virchows Arch. 2003;443:115–121
  54. Gulmann C, Butler D, Kay E, Grace A, Leader M. Biopsy of a biopsy: validation of immunoprofiling in gastric cancer biopsy tissue microarrays. Histopathology. 2003;42:70–76
  55. Fernebro E, Dictor M, Bendahl PO, Fernö M, Nilbert M. Evaluation of the tissue microarray technique for immunohistochemical analysis in rectal cancer. Arch Pathol Lab Med. 2002;126:702–705
  56. Camp RL, Charette LA, Rimm DL. Validation of tissue microarray technology in breast carcinoma. Lab Invest. 2000;80:1943–1949
  57. Gulmann C, O’Grady A. Tissue microarrays: an overview. Curr Diagn Pathol. 2003;9:149–154
  58. Goethals L, Perneel C, Debucquoy A, et al. A new approach to the validation of tissue microarrays. J Pathol. 2006;208:607–614
  59. Mucci NR, Akdas G, Manely S, Rubin MA. Neuroendocrine expression in metastatic prostate cancer: evaluation of high throughput tissue microarrays to detect heterogeneous protein expression. Hum Pathol. 2000;31:778
  60. Richter J, Wagner U, Kononen J, et al. High-throughput tissue microarray analysis of cyclin E gene amplification and overexpression in urinary bladder cancer. Am J Pathol. 2000;157:787–794
  61. Schraml P, Kononen J, Bubendorf L, et al. Tissue microarrays for gene amplification surveys in many different tumor types. Clin Cancer Res. 1999;5:1966–1975
  62. Hager M, Kolbitsch C, Tiefenthaler W, Haufe H, Kemmerling R, Lucia Moser P. Tissue microarrays from renal cell tumors: exclusion criteria and rate of exclusion. Scand J Urol Nephrol. 2007;41:485–489
  63. Datta MW, Kahler A, Macias V, Brodzeller T, Kajdacsy-Balla A. A simple inexpensive method for the production of tissue microarrays from needle biopsy specimens: examples with prostate cancer. Appl Immunohistochem Mol Morphol. 2005;13:96–103
  64. Vogel UF, Bueltmann BD. Simple, inexpensive, and precise paraffin tissue microarrays constructed with a conventional microcompound table and a drill grinder. Am J Clin Pathol. 2006;126:342–348
  65. Vogel UF. The construction of high-density paraffin tissue microarrays with 0.43-mm-diameter paraffin tissue core biopsies is technically feasible. Virchows Arch. 2008;453:43–46
  66. Pan CC, Chen PC, Chiang H. An easy method for manual construction of high-density tissue arrays. Appl Immunohistochem Mol Morphol. 2004;12:370–372
  67. Kramer MW, Merseburger AS, Hennenlotter J, Kuczyk M. Tissue microarrays in clinical urology - technical considerations. Scand J Urol Nephrol. 2007;41:478–484
  68. Bubendorf L, Kononen J, Koivisto P, et al. Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res. 1999;59:803–806
  69. Moch H, Schraml P, Bubendorf L, et al. High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma. Am J Pathol. 1999;154:981–986
  70. Rimm DL, Camp RL, Charette LA, Olsen DA, Provost E. Amplification of tissue by construction of tissue microarrays. Exp Mol Pathol. 2001;70:255–264
  71. Conway C, Dobson L, O’Grady A, Kay E, Costello S, O’Shea D. Virtual microscopy as an enabler of automated/quantitative assessment of protein expression in TMAs. Histochem Cell Biol. 2008;130:447–463
  72. Battifora H. Assessment of antigen damage in immunohistochemistry. The vimentin internal control. Am J Clin Pathol. 1991;96:669–671
  73. Parsons M, Scott N, Kavi V, et al. Tissue microarray quality control prior to their use - results from an internation interobserver study. Summer meeting of the Pathological Society of Great Britain and Ireland, Glasgow, 2007.

PII: S1756-2317(09)00024-3

doi: 10.1016/j.mpdhp.2009.01.010

Diagnostic Histopathology
Volume 15, Issue 3 , Pages 142-150 , March 2009