Diagnostic Histopathology
Volume 15, Issue 5 , Pages 273-278, May 2009

Proliferating trichilemmal tumour

Yvonne Bury State Exam Med MD is a Specialist Registrar at the Department of Cellular Pathology, James Cook University Hospital, Middlesbrough, UK

Clive Bloxham MBBChir MRCP FRCPath is a Consultant Pathologist at the Department of Histopathology, University Hospital of North Durham, Durham, UK

published online 09 April 2009.

Abstract 

Cutaneous cysts represent a large proportion of the specimens submitted for histopathological examination and comprise a wide spectrum of entities. The less common keratinous cysts are of pilar or trichilemmal type and proliferating trichilemmal tumour is infrequent. Transitional changes between an ordinary trichilemmal cyst and proliferating trichilemmal (pilar) tumour are seen. These usually behave in a benign fashion according to their bland cytology and architecture, although occasional examples with frank malignancy have been reported, simulating squamous cell carcinoma. This paper reports two cases representing the full range in the spectrum of proliferating trichilemmal tumour, underlining the need to distinguish these lesions from squamous cell carcinoma of the head and neck region and highlighting difficulties regarding their terminology.

Keywords: pilar tumour, proliferating trichilemmal tumour, trichilemmal carcinoma, trichilemmal cyst, trichilemmal keratinization

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PII: S1756-2317(09)00038-3

doi:10.1016/j.mpdhp.2009.02.011

Diagnostic Histopathology
Volume 15, Issue 5 , Pages 273-278, May 2009