Diagnostic Histopathology RSS feed: Current Issue. This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section. Both the contributors and readership are seen as being International. The trend toward continuing education/accreditation has a strong influence in the shaping of the journal's content and is reflected in the inclusion of a self-assessment section. http://www.diagnostichistopathology.co.uk/?rss=yesElsevier Inc.en © 2009 Published by Elsevier Inc. All rights reserved. Diagnostic Histopathology1756-2317156June 2009 © 2009 Published by Elsevier Inc. All rights reserved. healthpermissions@elsevier.comhttp://www.diagnostichistopathology.co.uk/article/PIIS1756231709000991/abstract?rss=yesEditorial board10.1016/S1756-2317(09)00099-1Diagnostic Histopathology 15, 6 (2009)2009-06-01Diagnostic Histopathology2009-06-01156S1756-2317(09)X0007-1iihttp://www.diagnostichistopathology.co.uk/article/PIIS1756231709000632/abstract?rss=yesAbstract: A variety of verrucous and papillary lesions affect the oral mucosa. Those which are benign and reactive, for example squamous papilloma or verruciform xanthoma, usually present little diagnostic difficulty. However, dysplastic and malignant verrucous and papillary lesions are a much greater diagnostic challenge, not helped by confusing terminology. Papillary hyperplasia is a reactive inflammatory condition, whereas verrucous hyperplasia is a potentially malignant dysplasia, and probably part of the spectrum of verrucous carcinoma. Papillary carcinomas, at least in the oral context, are essentially verrucous hyperplasias. ‘Oral florid papillomatosis’ is an obsolete term synonymous with verrucous carcinoma. A ‘classical’ verrucous carcinoma, with an exo-/endo-phytic growth pattern, ‘pushing’ invasive front and intact basement membrane, is easily identified, but many exophytic verrucous hyperplasias also show endophytic growth. These can also reasonably be diagnosed as verrucous carcinoma. If the lesion shows more than focal, early invasive disruption of the basement membrane, it should be diagnosed as a conventional squamous cell carcinoma.Papillary and verrucous lesions of the oral mucosaGareth J. Thomas, A. William Barrett10.1016/j.mpdhp.2009.03.006Diagnostic Histopathology 15, 6 (2009)2009-04-30Diagnostic Histopathology2009-04-30156S1756-2317(09)X0007-1Mini-Symposium: Oral and Maxillofacial Surgery279285http://www.diagnostichistopathology.co.uk/article/PIIS1756231709000668/abstract?rss=yesAbstract: Teeth are rarely submitted to general pathology departments, but on the rare occasions they are, the response is often confusion. This practically focused review aims to demystify the assessment of teeth, outlining the abnormalities which may be assessed without specialist equipment and others which may require specialist input. We will also provide a brief summary of some of the more common dental abnormalities and outline some forensic aspects of tooth pathology.Pathology of the teethKeith D. Hunter, Geoff Craig10.1016/j.mpdhp.2009.03.004Diagnostic Histopathology 15, 6 (2009)2009-04-30Diagnostic Histopathology2009-04-30156S1756-2317(09)X0007-1Mini-Symposium: Oral and Maxillofacial Surgery286295http://www.diagnostichistopathology.co.uk/article/PIIS1756231709000656/abstract?rss=yesAbstract: Oral squamous cell carcinoma (OSCC) is a common malignancy with an increase in incidence reported in some developing countries. Although the aetiological risk factors are well documented and advances have been made in the different treatment modalities, the mortality and morbidity of OSCC have not improved significantly over the last decades. The histopathologist is an important member of the multidisciplinary team responsible for the management of OSCC patients. This review will discuss the different histological subtypes of OSCC as well as other pathological features that can influence the behaviour of OSCC and should be included in a histopathology report.Surgical pathology of oral cancerWillie F.P. van Heerden, Andre W. van Zyl10.1016/j.mpdhp.2009.03.003Diagnostic Histopathology 15, 6 (2009)2009-04-30Diagnostic Histopathology2009-04-30156S1756-2317(09)X0007-1Mini-Symposium: Oral and Maxillofacial Surgery296302http://www.diagnostichistopathology.co.uk/article/PIIS1756231709000644/abstract?rss=yesAbstract: Odontogenic tumours can pose significant diagnostic challenges for the pathologist because of their relatively low incidence, somewhat overlapping histology and subtle differentiating features. Despite similar histologies, the biological behaviour and appropriate therapy differ significantly between entities and accurate diagnosis is therefore essential. This article reviews the most common and important odontogenic tumours and highlights key features that will assist the pathologist to identify and appropriately classify these lesions. In addition, several new concepts of classification are discussed and important new developments in our understanding of the biology of these lesions are highlighted.Current concepts of odontogenic tumoursRichard C.K. Jordan, Paul M. Speight10.1016/j.mpdhp.2009.03.002Diagnostic Histopathology 15, 6 (2009)2009-04-30Diagnostic Histopathology2009-04-30156S1756-2317(09)X0007-1Mini-Symposium: Oral and Maxillofacial Surgery303310http://www.diagnostichistopathology.co.uk/article/PIIS1756231709000620/abstract?rss=yesAbstract: A wide range of lesions arise from the intra-oral salivary glands, which present a diagnostic challenge to specialists and generalists alike. Of the salivary neoplasms, pleomorphic adenoma is the commonest, but its morphological diversity may bring several other entities to mind, notably polymorphous low-grade adenocarcinoma, particularly in a small incisional biopsy. Polymorphous low grade adenocarcinoma in turn shares features with adenoid cystic carcinoma. When the differential diagnosis includes these three tumours, immunohistochemistry can assist in the face of overlapping morphology. The other salivary neoplasms most likely to be encountered in the oral cavity are canalicular adenoma, mucoepidermoid carcinoma and acinic cell carcinoma. Of the non-neoplastic conditions, necrotizing sialometaplasia is most likely to be misdiagnosed as neoplastic on both clinical and histological grounds. However, careful consideration of the clinicopathological features of an adequate tissue specimen will enable correct diagnosis.Diagnostic difficulties in lesions of the minor salivary glandsPaul M. Speight, A. William Barrett10.1016/j.mpdhp.2009.03.001Diagnostic Histopathology 15, 6 (2009)2009-04-30Diagnostic Histopathology2009-04-30156S1756-2317(09)X0007-1Mini-Symposium: Oral and Maxillofacial Surgery311317http://www.diagnostichistopathology.co.uk/article/PIIS175623170900067X/abstract?rss=yesAbstract: Synchronous development of a colonic adenocarcinoma and lymphoma is extremely rare, with only a few cases reported in the literature. We report a case of a marginal zone B-cell lymphoma, which was incidentally diagnosed in a colonic resection for adenocarcinoma in a 77-year-old woman. It is important to be aware of the association, so as not to regard all lymphoid infiltrates surrounding a carcinoma as being reactive in nature.Synchronous adenocarcinoma and marginal zone B-cell lymphoma of the colon: a case reportNeil Sahasrabudhe, Nitin Khirwadkar, Richard Prescott10.1016/j.mpdhp.2009.03.005Diagnostic Histopathology 15, 6 (2009)2009-04-30Diagnostic Histopathology2009-04-30156S1756-2317(09)X0007-1Instructive Cases318322