An update on cutaneous tumours with neural differentiation

Published:November 10, 2021DOI:https://doi.org/10.1016/j.mpdhp.2021.10.004

      Abstract

      Cutaneous peripheral nerve sheath tumours are diverse proliferations of neuroectodermal origin ranging from benign, atypical to clearly malignant. In this update we review the clinico-pathological features supplemented by recent molecular genetic data of a variety of peripheral nerve sheath tumours arising primarily in the skin, including epithelial sheath neuroma, nerve sheath myxoma, schwannoma variants, neurofibroma variants, hybrid tumours, perineurioma, malignant melanotic schwannian tumour and malignant peripheral nerve sheath tumour (classical and epithelioid). Particular emphasis is also given to the differential diagnosis of these proliferations.

      Keywords

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